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Cymbalta Options to Take into account — Talkspace

Printed on: 30 Nov 2023

Alternatives to Cymbalta

Cymbalta (duloxetine) is a typical antidepressant for treating despair and nervousness. It’s additionally typically prescribed for diabetic peripheral neuropathy and different medical circumstances that trigger ache, like arthritis, fibromyalgia, and persistent again ache. Cymbalta is in a category of medicine referred to as serotonin-norepinephrine reuptake inhibitors (SNRIs). SNRIs stability norepinephrine and serotonin ranges — neurotransmitters related to temper regulation and application — within the mind.

Whereas Cymbalta might be very efficient for some individuals, it’s not at all times the correct remedy for everybody. It would trigger undesirable Cymbalta negative effects, antagonistic drug interactions, not be efficient in relieving signs, otherwise you may simply be in search of pure options to Cymbalta use. Holistic therapy choices have gotten extra interesting and acquainted, whether or not mixed with remedy or remedy or when used independently. 

No matter your purpose is for trying into Cymbalta options, we’re diving into every little thing you’ll want to learn about pure treatments and different medicine much like Cymbalta. 

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Different Medicines to Cymbalta

There are a selection of medicines that could be viable options to Cymbalta for despair or different circumstances. Since each drug has distinctive traits, advantages, dangers, and negative effects, exploring every choice and checking with a healthcare supplier is important earlier than switching from Cymbalta.

1. Lexapro 

Lexapro (escitalopram) is an alternative choice to Cymbalta that is likely to be good for people who find themselves involved about Cymbalta’s results when used long-term. Lexapro is within the class of medicine known as selective serotonin reuptake inhibitors (SSRIs), which work by rising serotonin ranges within the mind to reinforce temper. There are a lot of features to think about when taking a look at Cymbalta vs Lexapro.

Variations between Cymbalta and Lexapro: 

  • Cymbalta is a serotonin and norepinephrine reuptake inhibitor (SNRI) whereas Lexapro is a selective serotonin reuptake inhibitor (SSRI).
  • Cymbalta is FDA-approved to deal with extra circumstances than Lexapro.
  • There is likely to be fewer antagonistic negative effects of Lexapro than Cymbalta.
  • In some research, Lexapro was more practical in treating main depressive dysfunction (MDD).

Similarities between Cymbalta and Lexapro: 

  • Each can deal with main depressive dysfunction (MDD) and nervousness
  • Each medicine shouldn’t be used with anything that will increase serotonin ranges.
  • Cymbalta and Lexapro shouldn’t be used with NSAIDs or different medicine that may trigger bleeding.

2.Effexor (venlafaxine)

Effexor is likely to be an excellent choice to discover because it’s one of many medicine much like Cymbalta. As a result of they’re in the identical class of antidepressants — SNRIs — they work equally.

Nonetheless, it’s vital to notice that Effexor could trigger important blood stress adjustments in comparison with different antidepressants. So, monitoring your BP frequently and consulting a medical skilled when taking this drug is essential. 

Variations between Cymbalta and Effexor: 

  • Cymbalta is used to deal with extra medical circumstances.
  • Effexor might be an choice to deal with panic dysfunction and social nervousness dysfunction.
  • Effexor is extra more likely to lower intercourse drive as a aspect impact.
  • Cymbalta is stronger and can be utilized in decrease doses.

Similarities between Cymbalta and Effexor: 

  • Cymbalta and Effexor are each SNRIs.
  • Each medicine can deal with MDD and generalized nervousness dysfunction (GAD).
  • Shared negative effects embody dry mouth, drowsiness, lack of urge for food, and nausea.
  • Neither drug must be used along with monoamine oxidase inhibitors (MAOIs).

3. Prozac (fluoxetine)

Prozac is a typical and in style antidepressant remedy within the SSRI class of medicine. It’s prescribed to deal with main depressive dysfunction and obsessive-compulsive dysfunction. It’s additionally authorised to deal with the consuming dysfunction bulimia and panic dysfunction in adults.

Variations between Cymbalta and Prozac:

  • They’re in numerous lessons of medicine — Cymbalta is an SNRI and Prozac is an SSRI.
  • Prozac is authorised to deal with extra psychological well being circumstances.
  • Prozac can be utilized to deal with some disordered consuming circumstances.
  • Cymbalta is authorised to deal with ache associated to some medical circumstances, whereas Prozac will not be.

Similarities between Cymbalta and Prozac:

  • Cymbalta and Prozac can be utilized to deal with main depressive dysfunction.
  • Research counsel that each medicine have comparable efficacy and security outcomes.

4. Wellbutrin (bupropion)

Wellbutrin is an antidepressant authorised to deal with main depressive dysfunction (MDD) and seasonal affective dysfunction (SAD). It’s additionally prescribed for smoking cessation. Within the norepinephrine and dopamine reuptake inhibitors (NDRIs) class of medicine, Wellbutrin has among the identical antagonistic results as Cymbalta, together with the potential to trigger dry mouth, dizziness, issue sleeping or insomnia, and nausea. 

Variations between Cymbalta and Wellbutrin:

  • Cymbalta and Wellbutrin belong to completely different lessons of medicine.
  • Cymbalta may cause diarrhea and fatigue; Wellbutrin typically doesn’t.
  • Wellbutrin is likely to be a greater choice for individuals who expertise weight achieve on Cymbalta.

Similarities between Cymbalta and Wellbutrin:

  • Each medicine are used to deal with sure forms of ache.
  • Each Cymbalta and Wellbutrin might be efficient in treating despair.
Drug Class of Medication Treatable Circumstances Frequent Facet Results
Cymbalta (duloxetine) SNRI Main depressive dysfunction
Basic nervousness dysfunction
Nerve ache attributable to diabetes
Persistent muscle and joint ache
Dry mouth
Lack of urge for food
Elevated sweating
Lexapro (escitalopram) SSRI Main depressive dysfunction
Generalized nervousness dysfunction
Dry mouth
Problem sleeping
Diarrhea or constipation
Sexual dysfunction
Dizziness or drowsiness
Effexor (venlafaxine) SNRI Despair
Generalized nervousness dysfunction
Panic dysfunction
Social nervousness dysfunction
Dry mouth 
Lack of urge for food
Blurred imaginative and prescient
Prozac (fluoxetine) SSRI Main depressive dysfunction
compulsive dysfunction
Panic dysfunction
Bipolar despair
Lack of urge for food
Problem sleeping
Wellbutrin (bupropion) NDRIs Despair
Seasonal have an effect on dysfunction
Smoking cessation
Sleep points
Dry mouth

Pure Options to Cymbalta

Medicines like Cymbalta can work properly for some individuals, however others may desire a pure various. Whether or not it’s to keep away from negative effects or since you favor a holistic method, there are a number of non-pharmaceutical Cymbalta options accessible.

6. Omega-3 fatty acids

Omega-3 fatty acids are recognized for coronary heart well being advantages and the flexibility to assist psychological well being. Omega-3s are essential to mind perform and efficiency, and a few analysis has proven they will cut back signs of despair. Omega-3s are discovered naturally in meals sources like salmon or they’re accessible as dietary supplements.

7. Vitamin D

Often known as the sunshine vitamin, Vitamin D can increase temper, which could make it a possible various to Cymbalta for despair. Research have discovered that folks with despair usually have low vitamin D ranges, so supplementing may assist.

8. L-theanine

L-theanine is a singular amino acid present in inexperienced tea leaves. It’s gained reputation lately because of the calming impact it could actually have on the physique and thoughts. In analysis, l-theanine has been proven to be efficient in stress aid, temper enhancement, and improved sleep high quality.

9. Way of life adjustments 

Adjusting your life-style by specializing in wholesome habits generally is a stunning various to Cymbalta that many individuals may not contemplate. Implement the next into your days to see for those who discover a discount in depressive signs and nervousness.

  • Work out frequently: Analysis reveals that getting the guts price up releases endorphins, referred to as the feel-good hormones. Even one thing so simple as strolling briskly each day can enhance your temper.
  • Eat wholesome: Attempt to eat a balanced weight loss plan stuffed with nutrient-rich meals. It could not remedy your despair, however it could actually assist naturally carry your temper.
  • Apply mindfulness: Aware actions like meditation and journaling can change your mindset and enhance your temper.
  • Search remedy: Numerous research have confirmed the improved efficacy of mixing remedy and drugs vs. utilizing one or the opposite alone.

“Remedy is a good way to develop perception into signs and prognosis. It helps to facilitate consciousness and understanding of the problems that the particular person is going through. You can too study well being coping methods to assist handle signs. Typically remedy and remedy are mixed to deal with the particular person and have a constructive end result.”

Talkspace therapist Bisma Anwar, LPC, LMHC

Issues for Switching to a Cymbalta Different

In case you’re contemplating switching from a drugs like Cymbalta to a special drug or a holistic therapy plan, there are a number of vital components to recollect. Discovering an appropriate various is simply attainable if it suits your distinctive wants and targets for enchancment.

Take into account the next:

  • Why do you need to transition from Cymbalta?
  • Do the negative effects of the drug outweigh any constructive outcomes?
  • Have you ever talked to your physician about different medicines you’re at present taking?

“It is very important work carefully along with your psychiatrist when switching medicines to keep away from Cymbalta withdrawal. Focus on and be open about your signs and considerations along with your suppliers so they’re conscious of how you might be doing.”

Talkspace therapist Bisma Anwar, LPC, LMHC

Discover the Proper Different with Talkspace 

In case you’re attempting to resolve whether or not to alter medicines or take a holistic method to your therapy plan — or for those who’re interested by combining drugs with remedy or non-pharmaceutical therapy choices — Talkspace is right here. 

Talkspace is a web based platform with a crew of psychological well being professionals who can present remedy, prescriptions, and drugs administration.

We provide telehealth from the consolation of your house as you make essential choices about your remedy and therapy plan. Our crew is right here that will help you navigate the complexities of remedy adjustments.


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